The ingredients in Melanodyne can help to regulate the balance of fluid in the body. Melanodyne contains natural diuretics like Dandelion, buchu leaf, juniper, uva ursi, horsetail, and hydrangea root which means it helps to increase urine production and promote the excretion of excess fluid from the body. Vitamin B6, an ingredient in Melanodyne, can help to reduce swelling in the body, which can help to alleviate edema. Horsetail extract, a supplement in Melandoyne, may help reduce swelling in the feet by increasing urine output, which can reduce excess fluid accumulation in the body. The herbal ingredients in Melanodyne work with the potassium and may assist in reducing water content in the blood.